1. Cell Separations and Sorting
    MA Witek, IM Freed, SA Soper
    Analytical Chemistry, 2020, 92, 1, 105-131.
    DOI: 10.1021/acs.analchem.9b05357
  2. Prediction of Blood-Based Biomarkers and Subsequent Design of Bisulfite PCR-LDR-qPCR Assay for Breast Cancer Detection
    MD Bacolod, J Huang, SF Giardina, PB Feinberg, AH Mirza, A Swistel, SA Soper, F Barany
    BMC Cancer, 20:85 (2020)
    DOI: 10.1186/s12885-020-6574-4
    PMCID: PMC6995062
  3. The Need for Rapid Therapeutic Efficacy Testing for Cancer Therapy
    DG Kaufman
    Experimental and Molecular Pathology, 113 (2020) 104382
    DOI: 10.1016/j.yexmp.2020.104382
  4. Label-free counting of affinity-enriched circulating tumor cells (CTCs) using a thermoplastic micro-Coulter counter (μCC)
    C Kong, M Hu, KM Weerakoon-Ratnayake, MA Witek, K Dathathreya, ML Hupert, SA Soper
    Analyst, 145 (5):1677-1696, 2020
    DOI: 10.1039/c9an01802f
    PMID: 31867587
  5. Reducing Ovarian Cancer Mortality through Early Detection: Approaches Using Circulating Biomarkers
    CV Trinidad, AL Tetlow, LE Bantis, AK Godwin
    Cancer Prev Res (Phila). 13 (3):241-252, 2020.
    DOI: 10.1158/1940-6207
    PMID: 32132118
  6. Visible Photorelease of Liquid Biopsy Markers Following Microfluidic Affinity-Enrichment
    TN Pahattuge, JM Jackson, R Digamber, H Wijerathne, V Brown, MA Witek, C Perera, RS Givens, BR Peterson, SA Soper
    Chemical Communications, 2020, 56, 4098-4101.
    DOI: 10.1039/C9CC09598E
    PMID: 32163053
  7. Microfluidic Device for On-Chip Immunophenotyping and Cytogenic Analysis of Rare Biological Cells
    KM Weerakoon-Ratnayake, S Vaidyanathan, N Larkey, K Dathathreya, M Hu, J Jose, S Mog, KJ August, AK Godwin, ML Hupert, MA Witek, SA Soper
    Cells, 2020 Feb 24; 9(2): 519.
    DOI: 10.3390/cells9020519
    PMCID: PMC7072755
  8. Single-Molecule Detection of Cancer Mutations Using a Novel PCR-LDR-qPCR Assay
    C Ruiz, J Huang, SF Giardina, PB Feinberg, AH Mirza, MD Bacolod, SA Soper, F Barany
    Human Mutation, 2020, 41:5
    DOI: 10.1002/humu.23987
    PMCID: PMC7160051
  9. Understanding of plasticity size-effect governed mechanical response and incomplete die filling in a microscale double-punch molding configuration
    B Zhang, MS Dodaran, S Shao, J Choi, S Park, W Meng
    International journal of Mechanical Sciences, 172, 15 April 2020, 105406
    DOI: 10.1016/j.ijmecsci.2019.105406
  10. An Integrated, Optofluidic System with Aligned Optical Waveguides, Microlenses, and Coupling Prisms for Fluorescence Sensing
    DS Park, BM Young, BH You, V Singh, SA Soper, MC Murphy
    IEEE Journal of Microelectromechanical Systems, 2020, 29(4):600-609.
    DOI: 10.1109/JMEMS.2020.3004374
  11. Robust, Transparent, Superhydrophobic Coatings Using Novel Hydrophobic/Hydrophilic Dual-sized Silica Particles
    X Zhao, DS Park, J Choi, S Park, SA Soper, MC Murphy
    Journal of Colloid and Interface Science, 2020, 574, 347-354.
    DOI: 10.1016/j.jcis.2020.04.065
    PMCID: PMC7256315
  12. Leakage Pressures for Gasketless Superhydrophobic Fluid Interconnects (GSFI) for Modular Lab-on-a-Chip Systems
    CR Brown, X Zhao, T Park, PC Chen, BH You, DS Park, SA Soper, A Baird, MC Murphy
    Microsystems & Nanoengineering, 2020, submitted.
  13. Solid-Phase XRN1 Reactions for RNA Cleavage: Application in Single-Molecule Sequencing
    US Athapattu, CA Amarasekara, AC Nagel, F Barany, SA Soper
    Nucleic Acids Research, 2020, submitted.
  14. Application of multiplex bisulfite PCR-LDR-qPCR assay in interrogating bioinformatically-identified, blood-based methylation markers for colorectal cancer
    MD Bacolod, AH Mirza, J Huang, SF Giardina, PB Feinberg, SA Soper, F Barany
    Journal of Molecular Diagnostics, 2020, 22(7):885-900.
    DOI: 10.1016/j.jmoldx.2020.03.009
  15. Diagnosis of Acute Ischemic Stroke using Extracellular Vesicles’ mRNA Cargo
    H Wijerathne, et al.
    Nature Communications, January 2020, submitted
  16. Diagnostic Tests of Stroke Diseases
    H Wijerathne, MA Witek, Ae Baird, SA Soper
    Expert Review of Molecular Diagnostics, January 2020, submitted
  17. Microfluidic gasketless interconnects sealed by superhydrophobic surfaces
    DS Park, X Zhao, SA Soper, MC Murphy

    JMEMS, 2020 (accepted) JMEMS-2020-0168
  18. Open‐Tubular Nanoelectrochromatography (OT‐NEC): Gel‐Free Separation of Single Stranded DNAs (ssDNAs) in Thermoplastic Nanochannels
    CA Amarasekara, US Athapattu, C Rathnayaka, J Choi, S Park, SA Soper
    Electrophoresis, 2020 (accepted)
    DOI: 10.1002/elps.202000109
  1. Nanohole Array Plasmonic Biosensors: Emerging Point-of-Care Applications
    A Prasad, J Choi, Z Jia, S Park, MR Gartia
    Biosensors and Bioelectronics, 130, 185-203 (2019).
    DOI: 10.1016/j.bios.2019.01.037
    PMCID: PMC6475599
  2. Time-Delayed Integration--Spectral Flow Cytometer (TDI-SFC) for Low-Abundance-Cell Immunophenotyping
    W Hu, SA Soper, JM Jackson
    Analytical Chemistry, 2019, 91, 7, 4656-4664.
    DOI: 10.1021/acs.analchem.9b00021
  3. Scalable fabrication of sub-10 nm polymer nanopores for DNA analysis
    J Choi, CC Lee, S Park
    Microsystems & Nanoengineering, 2019, 5:12.
    DOI: 10.1038/s41378-019-0050-9
    PMCID: PMC6453903
  4. Book Chapter in “Spectroscopy and Dynamics of Single Molecules” (Elsevier)
    Chapter 7 – Single molecule analysis in nanofluidics devices
    KM Weerakoon-Ratnayake, S Vaidyanathan, CA Amarasekara, CK Johnson, SA Soper
    August 2019, 335-377.
    DOI: 10.1016/B978-0-12-816463-1.00007-9
  5. Design and Fabrication of a Multi-scale fluidic Motherboard for a Universal Molecular Processing System (uMPS)
    DS Park, M Witek, X Zhao, Y Kang, K Dathathreya, SA Soper, MC Murphy
    Proceedings of the ASME IMECE 2019, Salt Lake City, UT, Nov 11-14, 2019. IMECE2019-11921
    DOI: 10.1115/IMECE2019-11921
  6. Targeted inhibition of histone deacetylase leads to suppression of Ewing sarcoma tumor growth through an unappreciated EWS-FLI1/HDAC3/HSP90 signaling axis
    Y Ma, M Baltezor, L Rajewski, J Crow, G Samuel, VS Staggs, KM Chastain, JA Toretsky, SJ Weir, AK Godwin
    J Mol Med (Berl). 97 (7):957-972. 2019
    DOI: 10.1007/s00109-019-01782-0
    PMCID: PMC6584050
  7. Detection of CTCs from Whole Blood of Lung Cancer Patients Using the Automated Liquid Scan
    R Muller, S Purushotham, P Diaz, A Bartakova, J Muller-Cohn, J Lu, V Cheung, R Melnychuk, J Barber-Singh, E Fabio, H Husain, MA Witek, M Zomorrodi, ML Hupert, SA Soper, JM Jackson, C Chen
    Cancer Research, 79 (13 Supplement) 3984-3984. 2019
    DOI: 10.1158/1538-7445.AM2019-3984


  1. Accurate, Predictable, Repeatable Micro-Assembly Technology for Polymer, Microfluidic Modules
    TY Lee, K Han, D Barrett, S Park, SA Soper, M Murphy
    Sens. Actuators, B 254, 1249-1258 (2018).
    DOI: 10.1016/j.snb.2017.07.189
    PMCID: PMC5844477
  2. Isolation of Circulating Plasma Cells from Blood of Patients Diagnosed with Clonal Plasma Cell Disorders using Cell Selection Microfluidics
    J Kamande, M Lindell, MA Witek, P Voorhees, SA Soper
    Integr. Biol. 10, 82-91, (2018).
    DOI: 10.1039/C7IB00183E
    PMCID: PMC5877822
  3. Molecular Profiling of Liquid Biopsy Samples for Precision Medicine
    CDM Campos, JM Jackson, MA Witek, SA Soper
    The Cancer Journal 24, 93-103 (2018).
    DOI: 10.1097/PPO.0000000000000311
    PMCID: PMC5880307
  4. Electrokinetic Transport Properties of Deoxynucleotide Monophosphates (dNMPs) through Thermoplastic Channels
    CE O’Neil, CA Amarasekara, KM Weerakoon-Ratnayake, B Gross, Z Jia, V Singh, S Park, SA Soper
    Analytica chimica acta 1027, 67-75 (2018).
    DOI: 10.1016/j.aca.2018.04.047
    PMCID: PMC6408931
  5. Patterned Electromagnetic Alignment of Magnetic Nanowires
    M Beheshti, J Choi, X Geng, E Podlaha-Murphy, S Park
    Microelectric Engineering 193, 71-78 (2018).
    DOI: 10.1016/j.mee.2018.02.021
    PMCID: PMC6159939
  6. Microfluidic-based Solid Phase Extraction of Cell Free DNA
    CDM Campos, S Thippalagamage, JM Jackson, MA Witek, DS Park, M Murphy, AK Godwin, SA Soper
    Lab Chip 18, 3459-3470 (2018).
    DOI: 10.1039/C8LC00716K
    PMCID: PMC6391159
  7. Fabrication of Polymeric Dual-scale Nanoimprint Molds Using a Polymer Stencil Membrane
    J Choi, Z Jia, S Park
    Microelectronic Engineering 199, 101-105 (2018).
    DOI: 10.1016/j.mee.2018.07.009
    PMCID: PMC6474418
  8. Selection of UV-resins for Nanostructured Molds for Thermal-NIL
    Z Jia, J Choi, S Park
    Nanotechnology 29, 365302 (2018).
    DOI: 10.1088/1361-6528/aacd33
    PMCID: PMC6532406
  9. Surface Charge Density Dependent DNA Capture Through Polymer Planar Nanopores
    Z Jia, J Choi, S Park
    ACS Applied Materials & Interfaces 2018, 10 (47), pp 40927-40937.
    DOI: 10.1021/acsami.8b14423
  10. Electrical Characteristics of Individual FeNiCo-Au Core-Shell Nanowires Integrated into Microelectrodes on Plastic Substrate
    M Beheshti, X Geng, J Choi, E Podlaha-Murphy, S Park
    TechConnect Briefs (Proceedings of Nanotech 18 Conference), Vol. 1 (2018) 172-175. (ISBN 978-0-9988782-2-5).
  11. Droplet Impinging Behavior on Surfaces with Wettability Contrasts
    B Farshchian, J Pierce, MS Beheshti, S Park, N Kim
    Microelectric Engineering 195, 50-56 (2018).
    DOI: 10.1016/j.mee.2018.03.019
    PMCID: PMC6159947
  12. Extracellular Vesicles (EVs) as Blood-Basesd Markers: Microfluidics for their Enrichment and Analysis
    SA Soper
    Abstracts of Papers of the American Chemical Society 2018, 255
  1. Discrete microfluidics for the isolation of circulating tumor cell subpopulations targeting fibroblast activation protein alpha and epithelial cell adhesion molecule
    MA Witek, RD Aufforth, H Wang, JW Kamande, JM Jackson, SR Pullagurla, ML Hupert, J Usary, WZ Wysham, D Hilliard, S Montgomery, V Bae-Jump, LA Carey, PA Gehrig, MI Milowsky, CM Perou, JT Soper, YE Whang, JJ Yeh, G Martin, SA Soper
    npj Precision Oncology 1 (1), 24
    DOI: 10.1038/s41698-017-0028-8
    PMCID: PMC5871807
  2. Staphylococcus aureus extracellular vesicles (EVs): surface-binding antagonists of biofilm formation
    H Im, S Lee, SA Soper, RJ Mitchell
    Mol Biosyst. 2017 Nov 21;13(12):2704-2714
    DOI: 10.1039/c7mb00365j
    PMCID: PMC5873579
  3. Materials and microfluidics: enabling the efficient isolation and analysis of circulating tumour cells
    JM Jackson, WA Witek, JW Kamande, SA Soper
    Chem Soc Rev. 2017 Jul 17;46(14):4245-4280
    DOI: 10.1039/c7cs00016b. Review.
    PMCID: PMC5576189
  4. Thermoplastic nanofluidic devices for biomedical applications
    KM Weerakoon-Ratnayake, CE O'Neil, FI Uba, SA Soper
    Lab Chip. 2017 Jan 31;17(3):362-381
    DOI: 10.1039/c6lc01173j. Review.
    PMCID: PMC5285477
  5. 3D nanomolding and fluid mixing in micromixers with micro-patterned microchannel walls
    B Farshchian, A Amirsadeghi, J Choi, DS Park, N Kim, S Park
    Nano Converg. 2017 4:4
    DOI: 10.1186/s40580-017-0098-x
    PMCID: PMC5332510
  6. The role of hydrophobic silane coating on Si stamps in nanoimprint lithography
    A Amirsadeghi, L Brumfield, J Choi, E Brown, JJ Lee, S Park
    J. Appl. Phys. 121 (4), 044909
    DOI: 10.1063/1.4974533
    PMCID: PMC5881421
  7. CD15+ granulocyte and CD8+ T lymphocyte based gene expression clusters for ischemic stroke detection
    MG Adamski, Y Li, E Wagner, C Seales-Bailey, N Bennett, H Yu, MC Murphy, SA Soper, AE Baird
    Medical Research Archives, [S.l.], v. 5, n. 11, Nov. 2017
    DOI: 10.18103/mra.v5i11.1597
  8. Polymer-based Nanosensors using Flight-Time Identification of Mononucleotides for Single-Molecule Sequencing
    SA Soper, S Park, E Podlaha-Murphy
    Abstracts of Papers of the American Chemical Society 2017, 254
  1. Characterization of Activated Cyclic Olefin Copolymer: Effects of Ethylene/Norbornene Content on the Physiochemical Properties
    CE O’Neil, S Taylor, K Ratnayake, S Pullagurla, V Singh, SA Soper
    Analyst, 2016, 141, 6521-6532
    DOI: 10.1039/C6AN01448H
    PMCID: PMC5354357
  2. Interrogating Surface Functional Group Heterogeneity of Activated Thermoplastics Using Super-Resolution Fluorescence Microscopy
    CE O’Neil, JM Jackson, SH Shim, SA Soper
    Anal. Chem., 2016, 88 (7), pp 3686-3696
    DOI: 10.1021/acs.analchem.5b04472
    PMCID: PMC5546217
  3. Electrophoretic Separation of Single Particles Using Nanoscale Thermoplastic Columns
    KM Weerakoon-Ratnayake, FI Uba, NJ Oliver-Calixte, SA Soper
    Anal. Chem., 2016, 88 (7), pp 3569-3577
    DOI: 10.1021/acs.analchem.5b04065
    PMCID: PMC5555359
  4. Microfluidics for the Detection of Minimal Residual Disease in Acute Myeloid Leukemia Patients using Circulating Leukemic Cells Selected from Blood
    JM Jackson, JB Taylor, MA Witek, SA Hunsucker, JP Waugh, Y Fedoriw, TC Shea, SA Soper, PM Armistead
    Analyst, 2016, 21;141 (2): 640-51
    DOI: 10.1039/c5an01836f
    PMCID: PMC4701594
  5. Cancer: a Global Concern that Demands New Detection Technologies
    SA Soper, A Rasooly
    Analyst, 2016, 141, 367-370
    DOI: 10.1039/C5AN90101D
    PMCID: PMC4777894
  6. Improved Clinical Sensitivity Detection of Circulating Tumor Cell Assays using a Dual Selection Strategy in Women with Epithelial Ovarian Cancer
    WZ Wysham, MA Witek, SA Soper, VL Bae-Jump
    Gynecologic Oncology, 2016, vol 141, Supplement 1, 138
    DOI: 10.1016/j.ygyno.2016.04.364
  7. Book Chapter in “Circulating Tumor Cells: Isolation and Analysis” (John Wiley & Sons, Inc)
    Sinusoidal Microchannels with High Aspect Ratios for CTC Selection and Analysis
    JM Jackson, MA Witek, SA Soper
    April 2016, 85-119
    DOI: 10.1002/9781119244554.ch4
  8. Effect of Different Fluids on Rectified Motion of Leidenfrost Droplets on Micro/Sub-Micron Ratchets
    JT Ok, J Choi, E Brown, S Park
    Microelectronics Engineering 158, 130-134 (2016)
    DOI: 10.1016/j.mee.2016.04.018
    PMCID: PMC5053398
  9. Micron Level Placement of Nanowires via Real Time Observation Under Optical Microscope on a Desired Nanochannel for Nanosensors Application
    M Beheshti, S Park, J Choi, E Podlaha-Murphy
    ASME 2016 International Mechanical Engineering Congress and Exposition, Volume 10: Micro- and Nano-Systems Engineering and Packaging, Phoenix, Arizona, USA, November 11-17, 2016 (ISBN: 978-0-7918-5064-0), IMECE2016-67969 (4 Pages).
    DOI: 10.1115/IMECE2016-67969
  10. Digital Determination of Chemotherapeutic Drug-Induced Damage Sites in Single DNA Molecules using Nanofluidic Channels
    DG Kaufman, PD Chastain, SA Soper
    FASEB Journal 2016 30:1_supplement, 51.8-51.8
  11. Nanosensors using Flight-Time Identification of Mononucleotides for Single-Molecule DNA Sequencing
    SA Soper
    Abstracts of Papers of the American Chemical Society 2016, 252
  1. Investigation of Surface Charge and Electroosmotic Flow in Polymer Nanoslits and Nanochannels
    FI Uba, SR Pullagurla, N Sirasunthorn, J Wu, S Park, R Chantiwas, Y Cho, H Shin, SA Soper
    Analyst 140 (2015) 113-126.
    DOI: 10.1039/C4AN01439A
    PMCID: PMC4280799
  2. High Process Yield Rates of Thermoplastic Nanofluidic Devices using a Hybrid Thermal Assembly Technique
    FI Uba, B Hu, K Weerakoon-Ratnayake, N Oliver-Calixte, SA Soper
    LOC 15 (2015) 1038-1049. This appeared on the cover of the journal and has been a feature article in their blog.
    DOI: 10.1039/C4LC01254B
    PMCID: PMC4315742
  3. Enzymatic Cleavage of Uracil-Containing Single-Stranded DNA Linkers for the Efficient Release of Affinity-Selected Circulating Tumor Cells
    S Nair, JM Jackson, MA Witek, V Bae-Jump, PA Gehrig, WZ Wysham, PM Armistead, P Voorhees, SA Soper
    Chemical Communications 51 (2015) 3266-3269.
    DOI:  10.1039/C4CC09765C
    PMCID: PMC4552044
  4. Current and Future Bioanalytical Approaches to Stroke Assessment
    S Pullagurla, A Baird, SA Soper
    Bioanalysis 7 (2015) 1017-1035.
    DOI: 10.4155/bio.15.40
  5. Recent and Near-Future Advances in Nucleic Acid-based Diagnosis of Stroke
    AE Baird, SA Soper, S Pullagurla, M Adamski
    Expert Review of Molecular Diagnostics 5 (2015) 665-679.
    DOI: 10.1586/14737159.2015.1024660
  6. Rapid Assessment of Minimal Residual Acute Myeloid Leukemia from Peripheral Blood Using a Microfluidic Chip
    JM Jackson, J Taylor, MA Witek, SA Hunsucker, JP Waugh, YD Fedoriw, TC Shea, SA Soper, PM Armistead
    Blood 126 (2015) 1389.
    DOI: 10.1182/blood.V126.23.1389.1389
  7. Polymer Stamps for Nanoimprinting Nanofluidic Patterns
    J Wu, A Amirsadeghi, J Kim, S Park
    Journal of Nanoscience and Nanotechnology, 15 (2015) 471-474.
    DOI: 10.1166/jnn.2015.8390
  8. Synthesis and Characterization of ZIF-7 Membranes by In Situ Method
    S-J Noh, SP Yoon, J Han, S Park, J Kim
    Journal of Nanoscience and Nanotechnology, 15 (2015) 575-578.
    DOI: 10.1166/jnn.2015.8347
  9. Polymer-Based Fluidic Devices Integrated with Perforated Conical Nanopores in Freestanding Polymer Membrane
    J Choi, S Park
    Applied Mechanics and Materials, Vol. 752-753 (2015) 217-220.
    DOI: 10.4028/www.scientific.net/AMM.752-753.217
  10. The Influence of Micro Scale Ratchet Depth on the Motion of Leidenfrost Drop
    JT Ok, S Park
    Proceedings of the ASME 2015 International Mechanical Engineering Congress and Exposition (IMECE 2015), November 13-19, Houston, Texas, IMECE 2015-51922.
    DOI: 10.1115/IMECE2015-51922
  11. Reduction of Nanowire Agglomeration via an Intermediate Membrane in Nanowires Preparation for Nanosensors Application
    M Beheshti, S Park, J Choi, X Geng, E Podlaha-Murphy
    Proceedings of the ASME 2015 International Mechanical Engineering Congress and Exposition (IMECE 2015), November 13-19, Houston, Texas, IMECE 2015-53819.
    DOI: 10.1115/IMECE2015-53819
  12. Fabrication of Nanopores in Polymer Membranes using Nanoimprint Lithography for DNA Analysis
    J Choi, S Park
    19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), October 25-29, 2015, Gyongju, Korea, Pages 1112-1114.
  13. Electrophoretic Transport of Single DNA Nucleotides through Nanoslits: A Molecular Dynamics Simulation Study
    K Xia, BR Novak, KM Weerakoon-Ratnayake, SA Soper, DE Nikitopoulos, D Moldovan
    J. Phys. Chem. B, 2015, 119 (35), pp 11443-11458.
    DOI: 10.1021/acs.jpcb.5b02798
  14. Electrodeposition of Long Silver Nanowires in Highly Ordered Polymer-Based Template
    Z Jia, J Choi, S Park
    Proceedings of the ASME 2015 International Mechanical Engineering Congress and Exposition (IMECE 2015), November 13-15, Houston, Texas, IMECE 2015-52727.
    DOI: 10.1115/IMECE2015-52727
  15. Assembly of Polymer Microfluidic Components and Modules: Validating Models of Passive Alignment Accuracy
    BH You, DS Park, SD Rani, MC Murphy
    Journal of Microelectromechanical Systems, 2015, 24 (3), pp 634-650.
    DOI: 10.1109/JMEMS.2014.2339733
    PMCID: PMC6897507


Journal Cover